A recent investigations by Indian scientists at the Jadavpur University (West Bengal)-department of Food Technology and Biochemical Engineering, claim that the seeds of the big leaf mahogany tree, that are used to treat diabetes (a major metabolic disorder) in folk medicines, are non-toxic and safe natural product.
Diabetes mellitus or simply diabetes is a major metabolic disorder of recent time, It may trigger major complications such as hypoglycemia or cardiovascular problems.
Scientists, says, “They have clenching evidence that the seeds of the mahogany may be a potent, non-toxic, addition to the arsenal of safe natural products for the treatment of diabetes.” Local people of East Midnapore, West Bengal, use a crude concentrated extract of its seeds for diabetes treatment.
According to the Utpal Raychaudhuri, of the Jadavpur University, “In the animal model-based toxicity study, aqueous (water-based) extracts of the seeds were repeatedly given orally to groups of Wister albino rats for a period of 28 days, at levels of 0, 500, 1500 and 2000 mg per kg of body weight”.
According to the study published in 2012 in the Science and Culture Journal – a journal published by the Indian Science News Association – the extract did not produce any mortality in the animals even up to the dose level of 2,000 mg a kg. Also, the results of various blood and biochemical tests were normal. Further no changes were noticed in the liver, intestine, heart, kidney and stomach of the animals.
Plant constituents with the ability to prevent diabetes-related complications provide an encouraging prospect, but it is of paramount importance to test them for any toxic effects. One of such plants is the big leaf Mahogany (Swietenia macrophylla) – a beautiful, lofty, evergreen tree native to central America, Mexico, south America and India. The mahogany seeds are also known as “sky fruit” seeds to those who are native to the areas where mahogany trees grow, are familiar with taking these seeds as part of a varied and healthful diet.
The seeds contain: 33 types of flavonoids (These flavonoids in the seed directly aid in improving circulation), 27 types of saponins (are good for heart) making them even more nutritionally rich that other nutrient-dense plants, such as their relative ginseng. This combination of nutrients in the mahogany seed make it a good natural treatment to encourage good heart health and better circulation. They also contain various vitamins, minerals, proteins and fatty acids that are necessary to healthy body function.
The seeds of the big leaf mahogany may, therefore, be a potent non-toxic addition to the arsenal of safe natural products in the battle against diabetes.